Nov 8, 2025
12
Panama City, Panama
Miami, FL
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Jade
Starting Price
$1,920
Nov 17, 2025
31
Fort Lauderdale, FL
Buenos Aires, Argentina
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Holland America Line
Cruise Ship
Oosterdam
Starting Price
$4,600
Dec 20, 2025
15
Panama City, Panama
New York (Manhattan), NY
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Jade
Starting Price
$2,720
Dec 22, 2025
8
Fort Lauderdale, FL
Puerto Caldera, Costa Rica
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Crystal
Cruise Ship
Crystal Serenity
Starting Price
$4,120
Dec 27, 2025
11
Colon, Panama
Lima (Callao), Peru
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Windstar Cruises
Cruise Ship
Star Pride
Starting Price
$5,350
Jan 5, 2026
16
Fort Lauderdale, FL
Los Angeles (San Pedro), CA
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Princess Cruises
Cruise Ship
Coral Princess
Starting Price
$3,450
Jan 6, 2026
13
Fort Lauderdale, FL
Lima (Callao), Peru
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Silversea
Cruise Ship
Silver Dawn
Starting Price
$10,980
Jan 6, 2026
15
Miami, FL
Lima (Callao), Peru
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Azamara
Cruise Ship
Azamara Onward
Starting Price
$4,550
Jan 7, 2026
11
Lima (Callao), Peru
Colon, Panama
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Windstar Cruises
Cruise Ship
Star Pride
Starting Price
$5,050
Jan 18, 2026
11
Colon, Panama
Lima (Callao), Peru
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Windstar Cruises
Cruise Ship
Star Pride
Starting Price
$5,070
Jan 29, 2026
11
Lima (Callao), Peru
Colon, Panama
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Windstar Cruises
Cruise Ship
Star Pride
Starting Price
$5,010
Feb 27, 2026
12
Miami, FL
Lima (Callao), Peru
Sailing Date
Nights
Departs from
Ends in
Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Jade
Starting Price
$2,240
Search Luxury & Expedition Cruise Departures to the Panama Canal
Nov 8, 2025
12
Panama City, Panama
Miami, FL
Norwegian Cruise Line
Norwegian Jade
$1,920
Nov 17, 2025
31
Fort Lauderdale, FL
Buenos Aires, Argentina
Holland America Line
Oosterdam
$4,600
Dec 20, 2025
15
Panama City, Panama
New York (Manhattan), NY
Norwegian Cruise Line
Norwegian Jade
$2,720
Dec 22, 2025
8
Fort Lauderdale, FL
Puerto Caldera, Costa Rica
Crystal
Crystal Serenity
$4,120
Dec 27, 2025
11
Colon, Panama
Lima (Callao), Peru
Windstar Cruises
Star Pride
$5,350
Jan 5, 2026
16
Fort Lauderdale, FL
Los Angeles (San Pedro), CA
Princess Cruises
Coral Princess
$3,450
Jan 6, 2026
13
Fort Lauderdale, FL
Lima (Callao), Peru
Silversea
Silver Dawn
$10,980
Jan 6, 2026
15
Miami, FL
Lima (Callao), Peru
Azamara
Azamara Onward
$4,550
Jan 7, 2026
11
Lima (Callao), Peru
Colon, Panama
Windstar Cruises
Star Pride
$5,050
Jan 18, 2026
11
Colon, Panama
Lima (Callao), Peru
Windstar Cruises
Star Pride
$5,070
Jan 29, 2026
11
Lima (Callao), Peru
Colon, Panama
Windstar Cruises
Star Pride
$5,010
Feb 27, 2026
12
Miami, FL
Lima (Callao), Peru
Norwegian Cruise Line
Norwegian Jade
$2,240
Search Luxury & Expedition Cruise Departures to the Panama Canal
SAILING DATE
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DEPARTS FROM
ENDS IN
CRUISE LINE
CRUISE SHIP
STARTING PRICE
The Panama Canal is one of the most iconic and engineering marvels in the world, connecting the Atlantic and Pacific Oceans. A cruise through the Panama Canal offers travelers a unique opportunity to witness this incredible feat of human ingenuity while also exploring the diverse cultures and landscapes of Central America.
For first-time visitors looking for a luxurious and unforgettable experience, a Panama Canal cruise is the perfect choice. From the comfort of a luxury cruise ship, travelers can enjoy stunning views of the canal, lush rainforests, and charming port cities along the way. Whether you're a history buff, nature lover, or simply seeking a relaxing getaway, a Panama Canal cruise has something for everyone.
On a Panama Canal cruise, passengers can expect to visit ports of call such as Panama City, Cartagena, Costa Rica, and more. Each destination offers its own unique attractions, from ancient ruins and colonial architecture to pristine beaches and vibrant markets. With a variety of shore excursions available, travelers can tailor their experience to suit their interests and preferences.
In addition to exploring the rich culture and history of Central America, passengers can also enjoy the luxurious amenities and services offered on board their cruise ship. From gourmet dining and spa treatments to live entertainment and enrichment programs, a Panama Canal cruise provides a truly indulgent experience for guests.
Overall, a Panama Canal cruise is a once-in-a-lifetime journey that combines the excitement of traversing one of the world's most famous waterways with the relaxation and luxury of a cruise vacation. Whether you're a seasoned traveler or embarking on your first cruise, a Panama Canal cruise is sure to exceed your expectations and leave you with lasting memories.
Top 10 Places to Visit on a Panama Canal Cruise
1. Panama City: Explore the historic Casco Viejo district, visit the Panama Canal Museum, and take a boat tour of the canal itself.
2. Cartagena, Colombia: Discover the colonial charm of this UNESCO World Heritage Site, including the iconic walled city and San Felipe Castle.
3. Costa Rica: Experience the biodiversity of Costa Rica with a visit to the rainforests, national parks, and wildlife reserves.
4. Huatulco, Mexico: Relax on the pristine beaches of this resort town, go snorkeling or scuba diving, and explore the local markets.
5. Puerto Quetzal, Guatemala: Visit the ancient Mayan ruins of Tikal, explore the colonial city of Antigua, and sample traditional Guatemalan cuisine.
6. Puntarenas, Costa Rica: Take a zip line tour through the rainforest, go horseback riding on the beach, or relax in the hot springs of Arenal.
7. Cabo San Lucas, Mexico: Enjoy the vibrant nightlife, go whale watching, or take a boat tour to the famous El Arco rock formation.
8. Puerto Vallarta, Mexico: Explore the charming old town, relax on the beaches, and indulge in local cuisine and shopping.
9. Panama Canal Transit: Experience the thrill of passing through the locks of the canal and marvel at the engineering feat of this historic waterway.
10. Colon, Panama: Visit the Panama Canal Expansion Observation Center, explore the historic Fort San Lorenzo, and shop for souvenirs at the local market.
Panama Canal
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